Kristen Berendzen, MD, PhD

Asst Professor In Residence

M_Psych-Core-Rsch

Kristen is a physician scientist and Assistant Professor at UCSF. She completed her MD and PhD training at UC San Diego and at the Salk Institute. Her graduate work in Andrew Dillin's lab focused on understanding cellular stress regulation with aging and proteotoxicity. She then moved up to the Bay Area for psychiatry residency at UCSF and joined Dev Manoli's lab for her postdoc to study the genetic regulation of social attachment behavior in the prairie vole.

Publications

Oxytocin receptor controls promiscuity and development in prairie voles.

bioRxiv : the preprint server for biology

Sharma R, Berendzen KM, Everitt A, Wang B, Williams G, Wang S, Quine K, Larios RD, Long KLP, Hoglen N, Sulaman BA, Heath MC, Sherman M, Klinkel R, Cai A, Galo D, Caamal LC, Goodwin NL, Beery A, Bales KL, Pollard KS, Willsey AJ, Manoli DS

The germline coordinates mitokine signaling.

Cell

Shen K, Durieux J, Mena CG, Webster BM, Tsui CK, Zhang H, Joe L, Berendzen KM, Dillin A

Understanding social attachment as a window into the neural basis of prosocial behavior.

Frontiers in neurology

Berendzen KM

The germline coordinates mitokine signaling.

bioRxiv : the preprint server for biology

Shen K, Durieux J, Mena CG, Webster BM, Kimberly Tsui C, Zhang H, Joe L, Berendzen K, Dillin A

Attachment across the lifespan: Examining the intersection of pair bonding neurobiology and healthy aging.

Neuroscience and biobehavioral reviews

Berendzen KM, Bales KL, Manoli DS

Oxytocin receptor is not required for social attachment in prairie voles.

Neuron

Berendzen KM, Sharma R, Mandujano MA, Wei Y, Rogers FD, Simmons TC, Seelke AMH, Bond JM, Larios R, Goodwin NL, Sherman M, Parthasarthy S, Espineda I, Knoedler JR, Beery A, Bales KL, Shah NM, Manoli DS

Rethinking the Architecture of Attachment: New Insights into the Role for Oxytocin Signaling.

Affective science

Berendzen KM, Manoli DS

Genetic Loss of Oxytocin Receptor Signaling Sex-Specifically Affects the Dynamics of Pair Bond Formation and Promiscuity in Prairie Voles.

Biological Psychiatry

Kristen Berendzen, Ruchira Sharma, Amanda Everitt, Rose Larios, Gina Williams, Shuyu Wang, Kim Long, Jeremy Willsey, Devanand Manoli

Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis.

Cell

Berendzen KM, Durieux J, Shao LW, Tian Y, Kim HE, Wolff S, Liu Y, Dillin A

Poster Number: EI 6 Metabolism, Mitochondrial Stress, and Aging: How Neuroendocrine Signaling Coordinates Metabolic State in Aging and Neurodegenerative Disease Models.

American Journal of Geriatric Psychiatry

Kristen Berendzen, Jenni Durieux, Andrew Dillin

Systemic stress signalling: understanding the cell non-autonomous control of proteostasis.

Nature reviews. Molecular cell biology

Taylor RC, Berendzen KM, Dillin A

A combined therapeutic approach for pyruvate dehydrogenase deficiency using self-complementary adeno-associated virus serotype-specific vectors and dichloroacetate.

Molecular genetics and metabolism

Han Z, Berendzen K, Zhong L, Surolia I, Chouthai N, Zhao W, Maina N, Srivastava A, Stacpoole PW

NMR investigation of metabolism in cultured human fibroblasts: Effects of PDC deficiency and DCA administration.

Mitochondrion

P.W. Stacpoole, N.E. Simpson, Z. Han, K.M. Berendzen, C.A. Sweeney, J.A. Oca-Cossio, I. Constantinidis

Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency.

Mitochondrion

K.M. Berendzen, D.W. Theriaque, J.J. Shuster, P.W. Stacpoole

Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate.

Molecular genetics and metabolism

Simpson NE, Han Z, Berendzen KM, Sweeney CA, Oca-Cossio JA, Constantinidis I, Stacpoole PW

Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency.

Mitochondrion

Berendzen K, Theriaque DW, Shuster J, Stacpoole PW

13C and 31P NMR investigation of pyruvate dehydrogenase complex (PDC)-deficient human fibroblasts.

The FASEB Journal

Nicholas Simpson, Zongchao Han, Kristen Berendzen, Carol Sweeney, Jose Oca-Cossio, Ioannis Constantinidis, Peter Stacpoole

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